We cordially invite you to attend the 2025 21th International Conference on Intelligent Computing (ICIC 2025) to be held during August 8-11, 2025, Ningbo, China. The conference will be financially supported by the Natural Science Foundation of China (Natural Science Foundation of China) The theme for this conference is Advanced Intelligent Computing Methodologies and Applications. Original contributions related to this theme are especially solicited, including theories, methodologies, and applications in science and technology. Topics covering industrial issues/applications and academic research into intelligent computing will be also welcome. All submissions will be peer-reviewed by experts on the basis of originality, significance and clarity, and only those papers presenting novel research results or successful innovative applications will be accepted for publication as Oral paper or Poster paper. The conference proceedings for those accepted and registered Oral papers will be published by Springer-Nature, including Lecture Notes in Computer Sciences (LNCS)/ Lecture Notes in Artificial Intelligence (LNAI)/ Lecture Notes in Bioinformatics (LNBI). Those accepted and registered Poster papers will be arranged into a fixed poster website (http://poster-openaccess.com/) for an official spreading.