We cordially invite you to attend the 2020 Sixteenth International Conference on Intelligent Computing (ICIC 2020) to be held during October 2-5, 2020, in Bari, Italy. The conference will be financially supported by the Natural Science Foundation of China (Natural Science Foundation of China). The theme for this conference is Advanced Intelligent Computing Methodologies and Applications. Original contributions related to this theme are especially solicited, including theories, methodologies, and applications in science and technology. Topics covering industrial issues/applications and academic research into intelligent computing will be welcome. The conference proceedings will be published by Springer Verlag, including Lecture Notes in Computer Sciences (LNCS)/ Lecture Notes in Artificial Intelligence (LNAI)/ Lecture Notes in Bioinformatics (LNBI). All submissions will be peer-reviewed by experts on the basis of originality, significance and clarity, and only those papers presenting novel research results or successful innovative applications will be accepted for publication. In addition, some high-quality papers sub-selected from all ICIC2020 submissions will be included into several SCI indexed international journals such as IEEE/ACM Transactions on Computational Biology and Bioinformatics (IEEE/ACM TCBB) and Neurocomputing. Cognitive Systems Research , BMC Genomics , BMC Bioinformatics , BMC Medical Informatics , BMC Medical Informatics and Decision Making , BioData Mining and Algorithms for Molecular Biology